CHEMISTRY 450 BIOCHEMISTRY I
Southern Connecticut State University
Dr. Jiongdong Pang
Jennings 323
Tel: (203) 392-6272
E-mail: pang@scsu.ctstateu.edu
Web Site: http://www.scsu.ctstateu.edu/~pang
Fall Semester 20XX
Prerequisite: CHE 260-261, Organic Chemistry I & II
Text:
Sons,
Inc. (1999)
Laboratory
Manual:
Course Overview:
Biochemistry
is a physical science that applied to biological problems. Biochemistry involves the study of
structure and function of the molecules that make up living cells and
organisms. Understanding the structural
properties of a molecule enables us to form hypotheses about its interaction
with other molecules and its function in a cell.
In
CHE 450-451, we will discuss the molecular aspects of the four major types of
biological molecules: proteins, nucleic acids, lipids and carbohydrates. Further topics include biological
equilibria, metabolic pathways, thermodynamics, kinetics, bioenergetics, and
the assembly of molecules into cellular structures such as membranes.
Final Course Evaluation:
Three
one-hour examinations 40%
Ten
in-class Quizzes 10%
Laboratory
grade 25%
Final
examination 25%
--------
100%
The
final grade will be determined by the percentage of points obtained. The actual grade will be based on the
Southern Connecticut State University grading scale with possible adjustment
for class average at the end of the semester (if necessary).
Please
remember that it is the policy of the Chemistry Department at Southern
Connecticut State University that, to receive a passing grade in CHE 450, you MUST
pass the laboratory portion of the course. A passing grade
for the laboratory portion of the course is a 60%.
Illness
and Absences:
If
you are absolutely unable to attend an examination due to illness or other
crisis, please leave a message on my voice mail at 392-6272 or in the
Departmental Office at 392-6260.
If you wish to take a make-up examination, you must provide me with a
medical excuse or other proof of illness.
The doctorıs note must include a diagnosis or statement that you were
incapable of taking the examination.
Laboratory:
The
Chemistry Department requires that everyone wear Safety Glasses while in the
laboratory, beginning with the first laboratory. If you show up for any laboratory period without Safety
Glasses, you will NOT be allowed to perform the experiment and you will receive
a zero grade for that experiment.
The proper Safety Glasses must meet OSHA regulations and can be
purchased at the Southern Connecticut State University Bookstore.
Course
Outline:
September
6 Review
of Organic Chemistry
September
9, 11, 13 & 16 Chapter
2: Chemical Equilibria: Acids,
Bases,
and Buffers
September
18, 20 & 23 Chapter
4: Amino Acids: Structure, Properties, and
Stereochemistry
September
25 &27 Chapter
5: Proteins: Primary Structure
October
4 Hour
Examination One
October
11, 14, 16, 18 & 21 Chapter
12: Enzyme Kinetics, Inhibition, and
Regulation
October 23 & 25 Chapter
8: Carbohydrates
October 28, 30, November 1 & 4 Chapter 13:
Introduction to Metabolism:
Thermodynamics and Bioenergetics
November
6 Chapter
14: Glucose Catabolism: Glycolysis
November
8 Hour
Examination Two
November
13 & 15 Chapter
16: Citric Acid Cycle
November
18 & 20 Chapter
17: Electron Transport and Oxidative
Phosphorylation
December
2, 4 & 6 Chapter
15, contıd
December
9 Hour
Examination Three
December
16 Final
Examination (Cumulative)