CHEMISTRY 451 BIOCHEMISTRY II
Southern Connecticut State University
Dr. Jiongdong Pang
Jennings 323 (203) 392-6272
E-mail: pang@scsu.ctstateu.edu
Spring Semester 20XX
Prerequisite: CHE 450 or 452, Biochemistry I
Text: Fundamentals of Biochemistry, Voet, Voet & Pratt (1999).
Laboratory Manual: Experiments in Biochemistry, A Hands-on Approach, by Farrell & Ranallo, Brooks/Cole. (2000)
Course Overview:
Biochemistry
is a physical science that applied to biological problems. Biochemistry involves the study of the
structure and function of the molecules that make up living cells. Understanding the structural properties
of a molecule enables us to form hypotheses about its interaction with other
molecules and its function in a cell.
CHE 451 is the second half of the two-semester biochemistry course. In CHE 451, we will focus on two major
types of biological macromolecules: lipids and nucleic acids. We will also discuss the building block
molecules used to construct them.
Further topics will include fatty acid and protein metabolism, the
assembly of macromolecules into cellular structures such as membranes,
receptors, and transport systems.
Final Course Evaluation:
Three
one-hour examinations 40%
Ten
announced quizzes 10%
The
final grade will be determined by the percentage of points obtained. The actual grade will be based on the
Southern Connecticut State University grading scale with possible adjustment
for class average at the end of the semester (if necessary).
Please
remember that it is the policy of the Chemistry Department at Southern
Connecticut State University that, to receive a passing grade in CHE 451, you MUST
pass the laboratory portion of the course. A passing grade
for the laboratory portion of the course is a 60%.
Illness
and Absences:
If
you are absolutely unable to attend an examination due to illness or other
crisis, please leave a message on my voice mail at 392-6272 or in the
Departmental Office at 392-6260.
If you wish to take a make-up examination, you must provide me with a
medical excuse or other proof of illness.
Laboratory:
The
Chemistry Department requires that everyone wear Safety Glasses while in the
laboratory, beginning with the first lab.
If you show up for any laboratory period without Safety Glasses, you
will NOT be allowed to perform the experiment and you will receive a zero grade
for that experiment. The proper
Safety Glasses must meet OSHA regulations and can be purchased at the
University Bookstore.
Course
Outline:
1/22
1/24 Chapter
9: Lipids: Classification and Lipid Bilayers
1/27
1/31 Chapter
10: Biological Membranes
2/3
2/19 Chapter
19: Lipid Metabolism
2/21 Exam
1
2/24
3/3 Chapter
19 contąd
3/5
3/7 Chapter
18: Photosynthesis
3/10 3/12 Chapter
20: Amino Acid Metabolism: Urea Cycle
3/14 3/17 Chapter
21: Mammalian Fuel Metabolism: Integration and
Regulation
3/19
4/2 Chapter
3: Nucleic Acids: Structure and Function
4/7 4/25 DNA, RNA and Protein Synthesis
Chapter 24: DNA Replication, Repair and Recombination
Chapter 25: Transcription and RNA Processing
Chapter 26: Translation
4/28
5/2 Special
Topics: Receptors and Signal Transduction
5/7 Special
Topics contąd
5/12 Final
Exam (Cumulative, ACS Test)